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Anti-DLG2 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-3348R-CY3)

Lieferant: Bioss

Beschreibung: PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

UOM: 1 * 100 µl

Aktion

N/A Stück

1-Boc-2,5-dihydro-3-methyl-1H-pyrrole 95%

Lieferant: Apollo Scientific

Beschreibung: 1-Boc-2,5-dihydro-3-methyl-1H-pyrrole 95%

BOC-N-Methyl-D-Alanin 97%

Artikel-Nr: (APOSOR960889-25G)

Lieferant: Apollo Scientific

Beschreibung: N-(tert-Butoxycarbonyl)-N-methyl-D-alanine 97%

UOM: 1 * 25 g

Aktion

N/A Stück

Midostaurin ≥98% (durch TLC)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Inhibitor of a variety of serine/threonine and tyrosine kinases, like protein kinase C (PKC), cyclic AMP-dependent protein kinase (PKA), S6 kinase, Akt (protein kinase B; PKB), epidermal growth factor receptor (EGFR) tyrosine kinase activity and others including KDR, VEGFR, PDGFR, c-kit and other receptor tyrosine kinases. Potently inhibits FLT-3 kinase including mutant forms found in acute myeloid leukemia in vitro and in vivo. Apoptosis inducer. Showed broad antiproliferative activity against various tumor cell lines. Selectively inhibits T lymphocyte production of TNF-α. Upregulates endothelial nitric oxide synthase (eNOS; NOS III). Abrogates tumor angiogenesis in vivo.

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