Sie suchten nach: 3-Fluor-L-tyrosin

Artikel-Nr: (BOSSBS-13667R-A680)

Lieferant: Bioss

Beschreibung: Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-6382R-A750)

Lieferant: Bioss

Beschreibung: The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-7597R-A488)

Lieferant: Bioss

Beschreibung: The RIPK5 gene encodes a dual serine/threonine and tyrosine protein kinase that is expressed in multiple tissues. Multiple alternatively spliced transcript variants have been found, but the biological validity of some variants has not been determined.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-1334R-A555)

Lieferant: Bioss

Beschreibung: Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-7850R-A488)

Lieferant: Bioss

Beschreibung: Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-7850R-A555)

Lieferant: Bioss

Beschreibung: Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-7850R-A647)

Lieferant: Bioss

Beschreibung: Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-1738R-A750)

Lieferant: Bioss

Beschreibung: c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-5109R-A647)

Lieferant: Bioss

Beschreibung: Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-3093R-A350)

Lieferant: Bioss

Beschreibung: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-3093R-A488)

Lieferant: Bioss

Beschreibung: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-5109R-A750)

Lieferant: Bioss

Beschreibung: Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-7597R-A680)

Lieferant: Bioss

Beschreibung: The RIPK5 gene encodes a dual serine/threonine and tyrosine protein kinase that is expressed in multiple tissues. Multiple alternatively spliced transcript variants have been found, but the biological validity of some variants has not been determined.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-3132R-A350)

Lieferant: Bioss

Beschreibung: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-3132R-A647)

Lieferant: Bioss

Beschreibung: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-5223R-A555)

Lieferant: Bioss

Beschreibung: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].

UOM: 1 * 100 µl

Aktion