Sie suchten nach: 3-Fluor-L-tyrosin

Artikel-Nr: (BOSSBS-15500R-A750)

Lieferant: Bioss

Beschreibung: LTK is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-13651R-A488)

Lieferant: Bioss

Beschreibung: APS (adapter molecule containing PH and SH2 domains), SH2-B and Lnk compose a family of adapter proteins, which contain a pleckstrin homology (PH) domain, an SH2 domain and a tyrosine phosphorylation site. Stimulation of B cell receptor (BCR) or T cell receptor (TCR) results in the phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of BCR, TCR and several substrates. APS, SH2-B and Lnk may bind to the ITAM domain of BCR and TCR. Lnk is tyrosine phosphorylated in response to TCR stimulation and APS has been shown to be tyrosine phosphorylated in response to BCR stimulation.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-11066R-A555)

Lieferant: Bioss

Beschreibung: The downstream of kinase family (Dok-1-7) are members of a class of “docking” proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-11066R-A350)

Lieferant: Bioss

Beschreibung: The downstream of kinase family (Dok-1-7) are members of a class of “docking” proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-6382R-A750)

Lieferant: Bioss

Beschreibung: The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-6164R-A750)

Lieferant: Bioss

Beschreibung: Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-7850R-A488)

Lieferant: Bioss

Beschreibung: Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-7850R-A555)

Lieferant: Bioss

Beschreibung: Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-7850R-A647)

Lieferant: Bioss

Beschreibung: Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-1738R-A750)

Lieferant: Bioss

Beschreibung: c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-5109R-A647)

Lieferant: Bioss

Beschreibung: Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-3093R-A350)

Lieferant: Bioss

Beschreibung: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-3093R-A488)

Lieferant: Bioss

Beschreibung: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-5109R-A750)

Lieferant: Bioss

Beschreibung: Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-6164R-A488)

Lieferant: Bioss

Beschreibung: Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-0016R-A750)

Lieferant: Bioss

Beschreibung: Neuronal Marker Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.

UOM: 1 * 100 µl

Aktion