Sie suchten nach: Chiral+Technologies

Lieferant: STEMCELL Technologies

Beschreibung: Vascular endothelial growth factor (VEGF) is a heparin-binding homodimeric glycoprotein involved in vasculogenesis and angiogenesis. VEGF binds to FLT1 (VEGFR-1) and KDR (VEGFR-2), and activates Raf/MEK/ERK and PI3K/AKT pathways (Ferrara <i>et al.</i>). VEGF exists in multiple isoforms that result from alternative splicing of VEGF mRNA in the terminal exon. Proximal splice-site selection in exon 8 results in pro-angiogenic VEGFxxx isoforms (xxx is the number of amino acids), whereas distal splice-site selection results in anti-angiogenic VEGFxxxb isoforms (Nowak <i>et al.</i>). VEGF plays an important role in neurogenesis both in vitro and in vivo (Storkebaum <i>et al.</i>). It has neurotrophic effects on neurons of the central nervous system, and it promotes growth and survival of dopaminergic neurons and astrocytes. VEGF also promotes growth and survival of vascular endothelial cells, monocyte chemotaxis, and colony formation by granulocyte-macrophage progenitor cells (Ferrara <i>et al.</i>). Various splice variants of VEGF exist, with different functions. For example, it has been shown that VEGF isoform VEGF-164(165) and not VEGF-120(121) induces inflammation, stimulates intracellular adhesion molecule (ICAM)-1 expression on endothelial cells, and induces chemotaxis of monocytes (Usui <i>et al.</i>).

Artikel-Nr: (STMC02690)

Lieferant: STEMCELL Technologies

Beschreibung: Serum-free culture supplement for expansion of human hematopoietic cells.

UOM: 1 * 1 mL

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Artikel-Nr: (STMC05120)

Lieferant: STEMCELL Technologies

Beschreibung: Serum-free medium for the differentiation of human ES and iPS cells to pancreatic progenitor cells.

UOM: 1 * 1 KIT

Aktion

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Artikel-Nr: (STMC100-0670)

Lieferant: STEMCELL Technologies

Beschreibung: The EBV (BZLF1) peptide pool is a lyophilised mixture of 59 peptides from trans-activator protein BZLF1 of Epstein-Barr virus (EBV; strain B95-8). BZLF1 is a DNA-binding protein that acts as a switch from latent infection to lytic infection. The pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 245 on BZLF1.

UOM: 1 * 1 KIT

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Lieferant: STEMCELL Technologies

Beschreibung: Interleukin 7 (IL-7) is a member of the type I cytokine family that is critical for T and B cell development and survival. It is produced by non-hematopoietic cells in the thymus, lymphoid organs, and by bone marrow stromal cells (Lundström <i>et al.</i>). IL-7 binds to a receptor composed of common gamma chain and IL-7Ra (CD127) and signals through the JAK/STAT and PI3K pathways. IL-7 regulates the survival of naïve and memory CD4+ and CD8+ T cells, γδ T cells, NK T cells, innate lymphoid cells, and T regulatory cells (Carrette and Surh), and provides signals to promote survival, proliferation, and differentiation during B cell development (Clark <i>et al.</i>; Corfe and Paige).

Artikel-Nr: (STMC36250)

Lieferant: STEMCELL Technologies

Beschreibung: Dulbecco's Modified Eagle's Medium (DMEM) with 4500 mg/l D-glucose.

UOM: 1 * 500 mL

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Artikel-Nr: (STMC100-1396)

Lieferant: STEMCELL Technologies

Beschreibung: Stimulating T cells with the HPV18 (L1) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. A lyophilised mixture of 140 peptides from major capsid protein L1 of human papillomavirus type 18 (HPV18), HPV18 (L1) Peptide pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 568 on L1. L1 enters the nuclei of host cells and can assemble into virus-like particles (Stauffer <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.

UOM: 1 * 1 LE

New Product Aktion

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Artikel-Nr: (BWRLBS7828)

Lieferant: Bioworld Technology

Beschreibung: Recombinant full length Human DAPK1.

UOM: 1 * 100 µG

Aktion

Artikel-Nr: (BWRLBS7228)

Lieferant: Bioworld Technology

Beschreibung: Recombinant full length Human UHRF2.

UOM: 1 * 100 µG

Aktion

Artikel-Nr: (BWRLBS7830)

Lieferant: Bioworld Technology

Beschreibung: Recombinant full length Human EZH2.

UOM: 1 * 100 µG

Aktion

Artikel-Nr: (BWRLBS7843)

Lieferant: Bioworld Technology

Beschreibung: Recombinant full length Human PROCR.

UOM: 1 * 100 µG

Aktion

Artikel-Nr: (BWRLBS7225)

Lieferant: Bioworld Technology

Beschreibung: Recombinant full length Human Smad4.

UOM: 1 * 100 µG

Aktion

Artikel-Nr: (BWRLBS1472)

Lieferant: Bioworld Technology

Beschreibung: Synthetic peptide, corresponding to amino acids 650-697 of Human SENP5.

UOM: 1 * 100 µG

Aktion

Artikel-Nr: (BWRLBS1504)

Lieferant: Bioworld Technology

Beschreibung: Synthetic peptide, corresponding to amino acids 210-260 of Human PRAS40.

UOM: 1 * 100 µG

Aktion

Artikel-Nr: (BWRLBS3747)

Lieferant: Bioworld Technology

Beschreibung: Synthetic peptide, corresponding to amino acids 241-290 of Human MEK-7.

UOM: 1 * 100 µG

Aktion

Artikel-Nr: (BWRLBS3737)

Lieferant: Bioworld Technology

Beschreibung: Synthetic peptide, corresponding to amino acids 571-620 of Human Rb.

UOM: 1 * 100 µG

Aktion