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Artikel-Nr: (BOSSBS-6970R-A647)
Lieferant: Bioss
Beschreibung: Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-6970R-FITC)
Lieferant: Bioss
Beschreibung: Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3645R-CY5)
Lieferant: Bioss
Beschreibung: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-3645R-CY5.5)
Lieferant: Bioss
Beschreibung: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-6820R-A647)
Lieferant: Bioss
Beschreibung: MAGEA5 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene.
UOM: 1 * 100 µl


Artikel-Nr: (USBIM3886-75A)
Lieferant: US Biological
Beschreibung: Anti-MHC Class 1 Chain-related Gene A Rabbit Polyclonal Antibody
UOM: 1 * 200 µl


Artikel-Nr: (USBIP9102-70J)
Lieferant: US Biological
Beschreibung: Anti-Protein Gene Product 9.5 Rabbit Polyclonal Antibody
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-5736R-CY5.5)
Lieferant: Bioss
Beschreibung: TACC2 is a conserved family of centrosome and microtubule interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is thought to affect the progression of breast tumors. Expression of this gene is also induced by erythropoietin.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-8026R-A555)
Lieferant: Bioss
Beschreibung: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is unknown. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-8026R-HRP)
Lieferant: Bioss
Beschreibung: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is unknown. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Artikel-Nr: (USBIT2010-04B)
Lieferant: US Biological
Beschreibung: Anti-T-Cell Death-Associated Gene 8 Rabbit Polyclonal Antibody
UOM: 1 * 50 µG


Artikel-Nr: (USBIC0115-03D)
Lieferant: US Biological
Beschreibung: Anti-Calcitonin Gene Related Peptide 2 Rabbit Polyclonal Antibody
UOM: 1 * 400 µG


Artikel-Nr: (BOSSBS-1145R-CY7)
Lieferant: Bioss
Beschreibung: This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-5827R-A680)
Lieferant: Bioss
Beschreibung: PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organisation, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11599R-CY5)
Lieferant: Bioss
Beschreibung: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-11587R-CY5)
Lieferant: Bioss
Beschreibung: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
UOM: 1 * 100 µl


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