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Artikel-Nr: (BOHLV1953-07)

Lieferant: Bohlender

Beschreibung: Exsikkatoren-Verbinder (Star-Exsikkatoren), Zur sicheren und festen Verbindung von gestapelten SICCO Exsikkatoren ohne Bohren. Beste hend aus vier Klammer-Paaren, je Paar eine Schraube mit Mutter, ein Sechskantschlüssel, Montageanleitung. Geeignet fü 1 * 1 ST

UOM: 1 * 1 ST

Aktion

Artikel-Nr: (PRSI56-139)

Lieferant: ProSci Inc.

Beschreibung: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

UOM: 1 * 400 µl

Aktion

Artikel-Nr: (PRSI56-827)

Lieferant: ProSci Inc.

Beschreibung: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

UOM: 1 * 400 µl

Aktion

Artikel-Nr: (PRSI91-954)

Lieferant: ProSci Inc.

Beschreibung: RSPO1 is a secreted protein,containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family. RSPO1 is required for the early development of gonads, regardless of sex. It has been found in mice only eleven days after fertilization. To induce cell proliferation, it acts synergistically with WNT4. They help stabilize beta catenin, which activates downstream targets. RSPO1 is necessary in female sex development. It augments the WNT/ beta catenin pathway to oppose male sex development. In critical gonadal stages, between six and nine weeks after fertilization, the ovaries upregulate it while the testes downregulate it. RSPO1 can potentially aid in the treatment of mucositis, which is characterized by inflammation of the oral cavity. This unfortunate condition often accompanies chemotherapy and radiation in cancer patients with head and neck tumors.

UOM: 1 * 50 µG

Aktion

Artikel-Nr: (PRSI33-744)

Lieferant: ProSci Inc.

Beschreibung: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.

UOM: 1 * 100 µG

Aktion

Artikel-Nr: (PRSI33-768)

Lieferant: ProSci Inc.

Beschreibung: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.

UOM: 1 * 100 µG

Aktion

Artikel-Nr: (SOVE836516-35)

Lieferant: TRESTON

Beschreibung: T-fu# 1850 1 * 1 ST

UOM: 1 * 1 ST

Aktion

Artikel-Nr: (SOVE836532-35)

Lieferant: TRESTON

Beschreibung: L-fu# 1850 1 * 1 ST

UOM: 1 * 1 ST

Aktion

Artikel-Nr: (SOVE836597-35)

Lieferant: TRESTON

Beschreibung: I-fu# 1850 1 * 1 ST

UOM: 1 * 1 ST

Aktion

Artikel-Nr: (8.18505.0005)

Lieferant: Merck

Beschreibung: 5-Fluoruracil zur Synthese, Sigma-Aldrich®

UOM: 1 * 5 g

Sicherheitsdatenblätter Aktion

Artikel-Nr: (MAYBRDR01185.1)

Lieferant: Thermo Scientific

Beschreibung: 1-(3,5-dichloro-2-hydroxyphenyl)-3-(2-fu 1 * 1 g

UOM: 1 * 1 g

Aktion

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Artikel-Nr: (SOVEC52007001)

Lieferant: TRESTON

Beschreibung: Standardmodul, T-Fu#, 780x60x1850, 1 * 1 ST

UOM: 1 * 1 ST

Aktion

Artikel-Nr: (ENZOALX480099G005)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Thymidylate synthetase inhibitor

UOM: 1 * 5 g

Aktion

Artikel-Nr: (APOSBIF0123-25G)

Lieferant: Apollo Scientific

Beschreibung: This pyrimidine analogue, is an antineoplastic agent.

UOM: 1 * 25 g

Aktion

Lieferant: Thermo Fisher Scientific

Beschreibung: 5-Fluoruracil 99%

Sicherheitsdatenblätter

Lieferant: Thermo Fisher Scientific

Beschreibung: 5-Fluoruracil ≥99%

Sicherheitsdatenblätter Zertifikate