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Beschreibung: Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6). Blood Group Lewis a is a carbohydrate determinant carried on both glycolipids and glycoproteins.

Artikel-Nr: BOSSBS-12870R-A350

UOM: 1 * 100 µl

Lieferant: Bioss

Aktion

Beschreibung: Mouse monoclonal [2-25LE] antibody to Blood Group Lewis b for IHC-P, WB and ELISA with samples derived from Human.

Artikel-Nr: ANTIA85997-100

UOM: 1 * 100 µG

Lieferant: ANTIBODIES.COM

New Product Aktion

Beschreibung: Mouse monoclonal [7LE] antibody to Blood Group Lewis a for IHC-P, WB and ELISA with samples derived from human.

Artikel-Nr: ANTIA85793-100

UOM: 1 * 100 µG

Lieferant: ANTIBODIES.COM

New Product Aktion

Beschreibung: Anti-Streptococcus Group B Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: BIRBORB23196-1

UOM: 1 * 1 mL

Lieferant: Biorbyt

Aktion

Beschreibung: Glycosyltransferases that mediate the region and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyse the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins. Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking. Blood Group Lewis a is a carbohydrate determinant carried on both glycolipids and glycoproteins.

Artikel-Nr: BOSSBS-12870R-A680

UOM: 1 * 100 µl

Lieferant: Bioss

Aktion

Beschreibung: Recognises a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Artikel-Nr: PRSI33-520

UOM: 1 * 100 µG

Lieferant: ProSci Inc.

Aktion

Beschreibung: Mouse monoclonal [SPM 522] to Blood Group Lewis a.

Artikel-Nr: ABCAAB231432-100

UOM: 1 * 100 µl

Lieferant: Abcam

Aktion

Beschreibung: Mouse monoclonal [SPM522] antibody to Blood Group Lewis a for Flow Cytometry, IF and IHC-P with samples derived from Human and Mouse.

Artikel-Nr: ANTIA250913-100

UOM: 1 * 100 µG

Lieferant: ANTIBODIES.COM

New Product Aktion

Beschreibung: Mouse monoclonal [3-3A] antibody to Blood Group Antigen A for IHC-P with samples derived from human.

Artikel-Nr: ANTIA248757-100

UOM: 1 * 100 µG

Lieferant: ANTIBODIES.COM

New Product Aktion

Beschreibung: Recognises a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Artikel-Nr: PRSI33-535

UOM: 1 * 100 µG

Lieferant: ProSci Inc.

Aktion

Beschreibung: High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Artikel-Nr: PRSI91-711

UOM: 1 * 50 µG

Lieferant: ProSci Inc.

Aktion

Beschreibung: Recognises a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Artikel-Nr: PRSI33-530

UOM: 1 * 100 µG

Lieferant: ProSci Inc.

Aktion

Beschreibung: High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilises nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.

Artikel-Nr: PRSI92-282

UOM: 1 * 50 µG

Lieferant: ProSci Inc.

Aktion

Beschreibung: Anti-Blood Group Antigen Precursor Rabbit Polyclonal Antibody (FITC (Fluorescein))

Artikel-Nr: BIRBORB102169-100

UOM: 1 * 100 µG

Lieferant: Biorbyt

Aktion

Beschreibung: Mouse monoclonal [7LE] antibody to Blood Group Lewis a for Flow Cytometry, IF and IHC-P with samples derived from Human and Mouse.

Artikel-Nr: ANTIA250869-100

UOM: 1 * 100 µG

Lieferant: ANTIBODIES.COM

New Product Aktion

Beschreibung: Mouse monoclonal [SPM522] antibody to Blood Group Lewis a for Flow Cytometry, IF and IHC-P with samples derived from human and mouse.

Artikel-Nr: ANTIA254093-100

UOM: 1 * 100 µG

Lieferant: ANTIBODIES.COM

New Product Aktion