Sie suchten nach: 2-Oxoglutars\\u00E4ure

Artikel-Nr: (A1138.0250)

Lieferant: PanReac AppliChem

Beschreibung: 2-Oxoglutarsäure

UOM: 1 * 250 g

Aktion

Artikel-Nr: (BOSSBS-1294R)

Lieferant: Bioss

Beschreibung: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-12565R-A647)

Lieferant: Bioss

Beschreibung: ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.

UOM: 1 * 100 µl

Aktion

Lieferant: Thermo Fisher Scientific

Beschreibung: 2-Oxoglutarsäure 98%

Sicherheitsdatenblätter

Artikel-Nr: (BOSSBS-12565R-HRP)

Lieferant: Bioss

Beschreibung: ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-12565R-A750)

Lieferant: Bioss

Beschreibung: ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumour DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-12565R-A680)

Lieferant: Bioss

Beschreibung: ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumour DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-1294R-A680)

Lieferant: Bioss

Beschreibung: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-4037R)

Lieferant: Bioss

Beschreibung: SLC25A11 catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-1294R-A555)

Lieferant: Bioss

Beschreibung: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-1294R-A350)

Lieferant: Bioss

Beschreibung: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-1294R-A647)

Lieferant: Bioss

Beschreibung: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-8176R-CY5.5)

Lieferant: Bioss

Beschreibung: The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Aktion

Lieferant: Thermo Fisher Scientific

Beschreibung: α-Ketoglutaric acid disodium salt dihydrate 99%

Sicherheitsdatenblätter

Artikel-Nr: (BOSSBS-8176R)

Lieferant: Bioss

Beschreibung: The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Aktion

Artikel-Nr: (BOSSBS-4037R-A488)

Lieferant: Bioss

Beschreibung: SLC25A11 catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.

UOM: 1 * 100 µl

Aktion