Sie suchten nach: Trimethoprim

Lieferant: Apollo Scientific

Beschreibung: This antibiotic is a dihydrofolate reductase inhibitor. It inhibits the conversion of bacterial dihydrofolic acid to tetrahydrofolic acid which is necessary for the synthesis of amino acids, etc. and ultimately DNA synthesis.

Zertifikate

Lieferant: Thermo Fisher Scientific

Beschreibung: Trimethoprim 98%

Sicherheitsdatenblätter Zertifikate

Lieferant: Thermo Fisher Scientific

Beschreibung: Trimethoprim

Sicherheitsdatenblätter Zertifikate

Lieferant: MP Biomedicals

Beschreibung: Trimethoprim is an antibacterial agent; a specific inhibitor of formylation; a dihydrofolate reductase inhibitor.
Trimethoprim is primarily used as an antibacterial agent. It has dihydrofolate reductase inhibitor activity with selectivity for the prokaryote enzyme. It is used to treat urinary tract infections, mild acute prostatitis, recurrent cystitis, asymptomatic bacteriuria during pregnancy and respiratory tract infections.
The combination of Trimethoprim and sulfamethoxazole interferes with the cellular metabolism of folic acid in the bacterial cell by blocking the biosynthesis of nucleotides. Trimethoprim binds to dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). THF is an essential precursor in the thymidine synthesis pathway and interference with this pathway inhibits bacterial DNA synthesis.